![]() The incidence of breast cancer in women has been increasing year by year female breast cancer has surpassed lung cancer as the most commonly diagnosed cancer, with an estimated 2.3 million new cases ( 2). It ranks first in the incidence of female cancer, and the mortality rate ranks fourth in China ( 1). The malignancy rate of these 273 lesions is 1.5% (4/273) (<2%), and the sensitivity reduced to 99.6%, the specificity increased from 4.41% to 45.3%, and the accuracy increased from 63.4% to 78.8%.Ĭonclusion: By constructing a nomogram, some patients can be downgraded to avoid unnecessary biopsy.Īccording to statistics, the number of new cases of breast cancer among Chinese women reached 0.42 million in 2020, accounting for 18% of the global breast cancer rate. Results: Of 458 BI-RADS 4A patients, 273 (59.6%) were degraded to category 3. Multivariable logistic regression was used to screen out the independent influencing parameters that affect the benign and malignant tumors, and the nomogram was constructed by R language to downgrade BI-RADS 4A patients to eligible category. Materials and Methods: A total of 1,717 patients were retrospectively analyzed who underwent preoperative ultrasound, mammography, and magnetic resonance examinations in our hospital from August 2019 to September 2020, and a total of 458 patients of category BI-RADS 4A (mean age, 47 years range 18–84 years all women) were included. Objectives: To downgrade BI-RADS 4A patients by constructing a nomogram using R software. 3Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.2College of Medicine, Kunming University of Science and Technology, Department of Ultrasound, The First People’s Hospital of Yunnan Province, Kunming, China.1Department of Ultrasound, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.Yamie Xie 1,2, Ying Zhu 1, Weimin Chai 3, Shaoyun Zong 2, Shangyan Xu 1, Weiwei Zhan 1 and Xiaoxiao Zhang 1*
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